Scientific Advisory Board

The SCI’s SAB is a board provides inputs and advices to director in all related ongoing and future projects of SCI. Current the SCI’s SAB members are:


    Sheng Ding, PhD
Senior Investigator, Gladstone Institute of Cardiovascular Disease
Professor of Pharmaceutical Chemistry, University of California, San Francisco

Dr. Ding has pioneered the development and application of innovative chemical approaches to stem cell biology and regeneration. His work has focused on discovering and characterizing novel small molecules that can control various cell fates and functions, including stem cell maintenance, activation, differentiation and reprogramming in various developmental stages and tissues.

Dr. Ding earned a bachelor’s degree in chemistry with honors from the California Institute of Technology in 1999, working with Robert H. Grubbs, PhD. In 2003, he earned a PhD in chemistry from The Scripps Research Institute, working with Peter G. Schultz, PhD.



Astar Winoto,Ph.D

Director of Cancer Research Laboratory and Professor of Immunology and Pathogenesis, UC Berkeley

He is interested in the molecular mechanisms of cell death (apoptosis and programmed necrosis), T cell development and innate immunity. We are using a combination of biochemical, molecular biological and mouse transgenic/gene targeting approaches in our studies.

Dr. Winoto earned a bachelor’s degree Molecular Biology, University of California, Berkeley in 1981. In 1986, he earned a PhD  from California Institute of Technology.  His Ph.D Thesis (with Leroy Hood) was Major Histocompatibility Complex Gene Mapping and T Cell Receptor Gene Organization and Repertoire.



Wen-Hwa Lee ,Ph.D
Counselor China Medical University, Taiwan

Wen-Hwa Lee is a Donald Bren Professor of Biomedicine at the University of California, Irvine School of Medicine’s Department of Biological Chemistry. Among his accomplishments, Dr. Lee is renowned for identifying a tumor-suppressor gene that plays a vital role in the cellular battle against cancer.

In the late 1980s, Dr. Lee identified and cloned a gene that would rapidly become a focus of major interest among cancer researchers. Known as the human retinoblastoma susceptibility gene (RB), it constituted a new class of gene that suppressed the growth of tumors. When functioning at proper levels, RB proteins control the division of normal cells. Although only retinoblastoma, an eye malignancy, had been directly linked to the loss of RB in cells, Dr. Lee and colleagues were able to show that this gene could also be a factor in other cancers.

In addition to pioneering research on tumor-suppressing genes, Dr. Lee has investigated why the repair mechanisms for DNA can fail and cause the subsequent accumulation of cancer-promoting mutations. Dr. Lee has particularly focused on the initial events that compromise the ability of a cell to maintain the integrity of its coding information. His laboratory has linked two breast cancer susceptibility genes, BRCA-1 and BRCA-2, to the process of DNA repair (

  Prof.Yufang Shi
Director of Institute of Health Sciences
Laboratory of Immunology and Adult Stem Cell

Yufang Shi is Director and Professor of the Institute of Health Sciences, Shanghai Institutes for Biological Sciences of Chinese Academy of Sciences, and Shanghai Jiao Tong University School of Medicine. He also holds a University Professor title at Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey. He received his Ph.D. in Immunology from University of Alberta in 1992. From 1995 to 2001, he was a faculty member at the American Red Cross Laboratory, Holland and George Washington University. His research team studies i) molecular mechanisms of activation-induced cell death in T cell subpopulations; ii) understanding how immunosuppression is mediated in mesenchymal stem cells; iii) tumor stroma and tumor immunology; and iv) psychoneuroimmunology. He is one of the editors of Cell Research and has served on editorial boards of Journal of Immunology, Oncogene, Journal of Biological Chemistry, Cellular and Molecular Immunology, and the American Journal of Translational Research.

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