Scientists at USC Davis showed that prolonged fasting cycles could induce stem cell-based regeneration of the hematopoietic system, in which damaged immune cells are killed and replace with new cells. What is the basic idea behind this? During prolonged fasting, human body will try to save energy to overcome starvation by some mechanism; such as recycling old and damaged immune cells. Furthermore, prolonged fasting period also reduce the production of PKA enzyme, an enzyme that needs to be turned off in order for the stem cells to enter regenerative mode.

For more information, please read:

Cheng, Chia-Wei, et al. "Prolonged Fasting Reduces IGF-1/PKA to Promote Hematopoietic-Stem-Cell-Based Regeneration and Reverse Immunosuppression." Cell Stem Cell 18.2 (2016): 291-292.

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