Genetic Modified Stem Cell Development of Genetically Modified (GM) iPSC as a source for the next generation of stem cell therapy and a cell-free therapeutic agent

In 2022, SCI initiated research to modify stem cells and overexpressed some genes to improve their functionality and mechanism of action. Genetically Modified-induced pluripotent stem cells (GM-iPSCs) are a type of stem cell that has been genetically modified to have specific traits or capabilities. These cells are created by taking adult cells or more mature cells, such as skin or blood cells, and reprogramming them to a pluripotent state, where they have the ability to differentiate into any cell

type in the body. The cells are then modified using genetic engineering techniques, such as CRISPR/Cas9, to introduce or alter specific genes or traits. This allows scientists to create cells with specific properties or functions, such as cells that produce therapeutic proteins or cells that are resistant to certain diseases. GM-iPSCs have significant potential for use in regenerative medicine